{"hits":{"hits":[{"id":"62612","metadata":{"pid":"62612","documentType":"coar:c_6501","title":[{"type":"bf:Title","mainTitle":[{"value":"Chemosensory adaptations of the mountain fly Drosophila nigrosparsa (Insecta: Diptera) through genomics' and structural biology's lenses.","language":"eng"}]}],"partOf":[{"document":{"title":"Scientific reports"},"numberingYear":"2017","text":"Scientific reports. - 2017"}],"abstracts":[{"value":"Chemoreception is essential for survival. Some chemicals signal the presence of nutrients or toxins, others the proximity of mating partners, competitors, or predators. Chemical signal transduction has therefore been studied in multiple organisms. In Drosophila species, a number of odorant receptor genes and various other types of chemoreceptors were found. Three main gene families encode for membrane receptors and one for globular proteins that shuttle compounds with different degrees of affinity and specificity towards receptors. By sequencing the genome of Drosophila nigrosparsa, a habitat specialist restricted to montane/alpine environment, and combining genomics and structural biology techniques, we characterised odorant, gustatory, ionotropic receptors and odorant binding proteins, annotating 189 loci and modelling the protein structure of two ionotropic receptors and one odorant binding protein. We hypothesise that the D. nigrosparsa genome experienced gene loss and various evolutionary pressures (diversifying positive selection, relaxation, and pseudogenisation), as well as structural modification in the geometry and electrostatic potential of the two ionotropic receptor binding sites. We discuss possible trajectories in chemosensory adaptation processes, possibly enhancing compound affinity and mediating the evolution of more specialized food, and a fine-tuned mechanism of adaptation.","language":"eng"}],"contribution":[{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Cicconardi F"},"affiliation":"Institute of Ecology, University of Innsbruck, Technikerstr. 25, 6020 Innsbruck, Austria.","text":"Cicconardi F"},{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Di Marino D"},"affiliation":"Department of Informatics, Institute of Computational Science, University of Italian Switzerland, Lugano, Switzerland.","controlledAffiliation":["Universit\u00e0 della Svizzera italiana"],"text":"Di Marino D"},{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Olimpieri PP"},"affiliation":"Department of Physics, Sapienza University of Rome, Rome, Italy.","text":"Olimpieri PP"},{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Arthofer W"},"affiliation":"Institute of Ecology, University of Innsbruck, Technikerstr. 25, 6020 Innsbruck, Austria.","text":"Arthofer W"},{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Schlick-Steiner BC"},"affiliation":"Institute of Ecology, University of Innsbruck, Technikerstr. 25, 6020 Innsbruck, Austria.","text":"Schlick-Steiner BC"},{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Steiner FM"},"affiliation":"Institute of Ecology, University of Innsbruck, Technikerstr. 25, 6020 Innsbruck, Austria.","text":"Steiner FM"}],"language":[{"type":"bf:Language","value":"eng"}],"provisionActivity":[{"type":"bf:Publication","startDate":"2017","statement":[{"type":"Date","label":[{"value":"2017-03-04"}]}],"text":{"default":"2017-03-04"}}],"identifiedBy":[{"type":"bf:Doi","value":"10.1038/srep43770"},{"type":"bf:Local","value":"28256589","source":"PMID"}],"identifiers":{"doi":["10.1038/srep43770"],"local":["28256589"]},"subjects":[{"label":{"value":["Adaptation, Physiological"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Animals"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Drosophila"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Drosophila Proteins"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Genomic Library"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Genomics"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Models, Molecular"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Multigene Family"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Phylogeny"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Protein Conformation"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Receptors, Cell Surface"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Receptors, Ionotropic Glutamate"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Receptors, Odorant"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Sequence Analysis, DNA"],"language":"eng"},"source":"MeSH"}],"oa_status":"gold","masked":"not_masked","_bucket":"610b2ede-3fed-4cfd-b796-c94ce3016cde","_files":[{"key":"fulltext.pdf","label":"Full-text","type":"file","order":1,"restriction":{"restricted":false,"date":null},"links":{"external":"https://www.nature.com/articles/srep43770.pdf","preview":null,"download":null},"thumbnail":"/documents/62612/files/fulltext-pdf.jpg"},{"key":"fulltext-pdf.txt","type":"fulltext"},{"key":"fulltext-pdf.jpg","type":"thumbnail"}],"_oai":{"id":"oai:sonar.ch:62612"},"permissions":{"read":true,"update":false,"delete":false},"permalink":"https://roar.hep-bejune.ch/global/documents/62612"},"links":{"self":"https://roar.hep-bejune.ch/api/documents/62612"},"created":"2021-02-06T03:15:03.545143+00:00","updated":"2025-10-24T21:03:07.130599+00:00"},{"id":"254090","metadata":{"pid":"254090","documentType":"coar:c_6501","title":[{"type":"bf:Title","mainTitle":[{"value":"Synthetic Biology-The Synthesis of Biology.","language":"eng"}]}],"partOf":[{"document":{"title":"Angewandte Chemie (International ed. in English)"},"numberingYear":"2017","text":"Angewandte Chemie (International ed. in English). - 2017"}],"abstracts":[{"value":"Synthetic biology concerns the engineering of man-made living biomachines from standardized components that can perform predefined functions in a (self-)controlled manner. Different research strategies and interdisciplinary efforts are pursued to implement engineering principles to biology. The \"top-down\" strategy exploits nature's incredible diversity of existing, natural parts to construct synthetic compositions of genetic, metabolic, or signaling networks with predictable and controllable properties. This mainly application-driven approach results in living factories that produce drugs, biofuels, biomaterials, and fine chemicals, and results in living pills that are based on engineered cells with the capacity to autonomously detect and treat disease states in\u2005vivo. In contrast, the \"bottom-up\" strategy seeks to be independent of existing living systems by designing biological systems from scratch and synthesizing artificial biological entities not found in nature. This more knowledge-driven approach investigates the reconstruction of minimal biological systems that are capable of performing basic biological phenomena, such as self-organization, self-replication, and self-sustainability. Moreover, the syntheses of artificial biological units, such as synthetic nucleotides or amino acids, and their implementation into polymers inside living cells currently set the boundaries between natural and artificial biological systems. In particular, the in\u2005vitro design, synthesis, and transfer of complete genomes into host cells point to the future of synthetic biology: the creation of designer cells with tailored desirable properties for biomedicine and biotechnology.","language":"eng"}],"contribution":[{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Ausl\u00e4nder S"},"affiliation":"Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058, Basel, Switzerland.","controlledAffiliation":["ETH Zurich"],"text":"Ausl\u00e4nder S"},{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Ausl\u00e4nder D"},"affiliation":"Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058, Basel, Switzerland.","controlledAffiliation":["ETH Zurich"],"text":"Ausl\u00e4nder D"},{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Fussenegger M"},"affiliation":"Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058, Basel, Switzerland.","controlledAffiliation":["ETH Zurich"],"text":"Fussenegger M"}],"language":[{"type":"bf:Language","value":"eng"}],"provisionActivity":[{"type":"bf:Publication","startDate":"2017","statement":[{"type":"Date","label":[{"value":"2016-12-13"}]}],"text":{"default":"2016-12-13"}}],"identifiedBy":[{"type":"bf:Doi","value":"10.1002/anie.201609229"},{"type":"bf:Local","value":"27943572","source":"PMID"}],"identifiers":{"doi":["10.1002/anie.201609229"],"local":["27943572"]},"subjects":[{"label":{"value":["bioengineering"],"language":"eng"}},{"label":{"value":["chemical biology"],"language":"eng"}},{"label":{"value":["genome engineering"],"language":"eng"}},{"label":{"value":["metabolic engineering"],"language":"eng"}},{"label":{"value":["synthetic biology"],"language":"eng"}},{"label":{"value":["Animals"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Biocompatible Materials"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Biofuels"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Cell Engineering"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Cell- and Tissue-Based Therapy"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Cell-Free System"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Genetic Engineering"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Genome"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Humans"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Interdisciplinary Studies"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Synthetic Biology"],"language":"eng"},"source":"MeSH"}],"oa_status":"closed","masked":"not_masked","_bucket":"29b3d129-7dec-438d-8645-48dfe0cf50bd","_oai":{"id":"oai:sonar.ch:254090"},"permissions":{"read":true,"update":false,"delete":false},"permalink":"https://roar.hep-bejune.ch/global/documents/254090"},"links":{"self":"https://roar.hep-bejune.ch/api/documents/254090"},"created":"2021-02-07T19:53:59.492201+00:00","updated":"2025-10-24T21:29:20.050921+00:00"},{"id":"228416","metadata":{"pid":"228416","documentType":"coar:c_6501","title":[{"type":"bf:Title","mainTitle":[{"value":"Synthetic biology--putting engineering into biology.","language":"eng"}]}],"partOf":[{"document":{"title":"Bioinformatics (Oxford, England)"},"numberingYear":"2006","text":"Bioinformatics (Oxford, England). - 2006"}],"abstracts":[{"value":"Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we review the case for this emerging discipline. Key aspects of an engineering approach are purpose-orientation, deep insight into the underlying scientific principles, a hierarchy of abstraction including suitable interfaces between and within the levels of the hierarchy, standardization and the separation of design and fabrication. Synthetic biology investigates possibilities to implement these requirements into the process of engineering biological systems. This is illustrated on the DNA level by the implementation of engineering-inspired artificial operations such as toggle switching, oscillating or production of spatial patterns. On the protein level, the functionally self-contained domain structure of a number of proteins suggests possibilities for essentially Lego-like recombination which can be exploited for reprogramming DNA binding domain specificities or signaling pathways. Alternatively, computational design emerges to rationally reprogram enzyme function. Finally, the increasing facility of de novo DNA synthesis-synthetic biology's system fabrication process-supplies the possibility to implement novel designs for ever more complex systems. Some of these elements have merged to realize the first tangible synthetic biology applications in the area of manufacturing of pharmaceutical compounds.","language":"eng"}],"contribution":[{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Heinemann M"},"affiliation":"ETH Zurich, Bioprocess Laboratory, Institute of Process Engineering Universit\u00e4tsstrasse 6, 8092 Zurich, Switzerland.","controlledAffiliation":["ETH Zurich"],"text":"Heinemann M"},{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Panke S"},"text":"Panke S"}],"language":[{"type":"bf:Language","value":"eng"}],"provisionActivity":[{"type":"bf:Publication","startDate":"2006","statement":[{"type":"Date","label":[{"value":"2006-09-07"}]}],"text":{"default":"2006-09-07"}}],"identifiedBy":[{"type":"bf:Doi","value":"10.1093/bioinformatics/btl469"},{"type":"bf:Local","value":"16954140","source":"PMID"}],"subjects":[{"label":{"value":["Animals"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Biotechnology"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Computational Biology"],"language":"eng"},"source":"MeSH"},{"label":{"value":["DNA"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Engineering"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Genetic Engineering"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Humans"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Internet"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Kinetics"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Models, Biological"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Protein Engineering"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Signal Transduction"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Software"],"language":"eng"},"source":"MeSH"},{"label":{"value":["Systems Biology"],"language":"eng"},"source":"MeSH"}],"oa_status":"bronze","masked":"not_masked","_bucket":"342169c5-5c8f-4c60-b936-dc47937f06c8","_files":[{"key":"fulltext.pdf","label":"Full-text","type":"file","order":1,"restriction":{"restricted":false,"date":null},"links":{"external":"https://academic.oup.com/bioinformatics/article-pdf/22/22/2790/497651/btl469.pdf","preview":null,"download":null},"thumbnail":"static/images/no-image.png"}],"_oai":{"id":"oai:sonar.ch:228416"},"permissions":{"read":true,"update":false,"delete":false},"permalink":"https://roar.hep-bejune.ch/global/documents/228416"},"links":{"self":"https://roar.hep-bejune.ch/api/documents/228416"},"created":"2021-02-07T14:35:33.566469+00:00","updated":"2025-10-24T23:05:14.569439+00:00"},{"id":"144834","metadata":{"pid":"144834","documentType":"coar:c_6501","title":[{"type":"bf:Title","mainTitle":[{"value":"Measuring Mountain Maladies","language":"eng"}]}],"partOf":[{"document":{"title":"High Altitude Medicine & Biology","publication":{"startDate":"2007-8","statement":"Mary Ann Liebert Inc"},"identifiedBy":[{"type":"bf:Issn","value":"1557-8682"}]},"numberingYear":"2007","numberingIssue":"3","numberingPages":"171-172","numberingVolume":"8","text":"High Altitude Medicine & Biology. - Mary Ann Liebert Inc. - 2007, vol. 8, no. 3, p. 171-172"}],"contribution":[{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Roach, Robert"},"affiliation":"Altitude Research Center, University of Colorado, Denver, Colorado.","text":"Roach, Robert"},{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Kayser, Bengt"},"affiliation":"Institut des sciences du mouvement et de la m\u00e9decine du sport, Facult\u00e9 de m\u00e9decine, Universit\u00e9 de Gen\u00e8ve, Geneva, Switzerland.","controlledAffiliation":["University of Geneva and HUG"],"text":"Kayser, Bengt"}],"language":[{"type":"bf:Language","value":"eng"}],"identifiedBy":[{"type":"bf:Doi","value":"10.1089/ham.2007.8301"},{"type":"bf:Issn","value":"1527-0297"}],"identifiers":{"doi":["10.1089/ham.2007.8301"],"issn":["1527-0297"]},"subjects":[{"label":{"value":["Public Health, Environmental and Occupational Health"],"language":"eng"}},{"label":{"value":["Physiology"],"language":"eng"}},{"label":{"value":["General Medicine"],"language":"eng"}}],"oa_status":"closed","masked":"not_masked","_bucket":"66c57fed-24a3-442e-80a7-584ac435021b","_oai":{"id":"oai:sonar.ch:144834"},"permissions":{"read":true,"update":false,"delete":false},"permalink":"https://roar.hep-bejune.ch/global/documents/144834"},"links":{"self":"https://roar.hep-bejune.ch/api/documents/144834"},"created":"2021-02-06T20:22:00.045878+00:00","updated":"2025-10-24T20:17:39.283920+00:00"},{"id":"328758","metadata":{"pid":"328758","documentType":"coar:c_7a1f","title":[{"type":"bf:Title","mainTitle":[{"value":"Limnimeter for mountain rivers","language":"eng"}]}],"abstracts":[{"value":"The objective of this thesis is to improve an existing or design a new sensor so that it can measure bedload height and water height of mountain rivers separately.","language":"eng"}],"contribution":[{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Biselx, John"},"text":"Biselx, John"},{"role":["dgs"],"agent":{"type":"bf:Person","preferred_name":"Moerschell, Joseph"},"text":"Moerschell, Joseph (degree supervisor)"}],"organisation":[{"pid":"hesso","code":"hesso","name":"SONAR|HES-SO","_files":[{"key":"HES_SO_Logo_RGB.png","size":15129,"bucket":"c0bb2b3c-dfa8-4935-be23-21e201e1e115","file_id":"59f0532f-7d20-4607-b9b4-976c8f52a365","checksum":"md5:925d081cc00cef2ba8fbb71b921b8aea","mimetype":"image/png","version_id":"6e1f503c-5f72-431f-b1a7-c0fc5d9066ea"}],"_bucket":"c0bb2b3c-dfa8-4935-be23-21e201e1e115","isShared":true,"description":[{"value":"SONAR|HES-SO regroupe les travaux de bachelor et master diffusables de plusieurs \u00e9coles de la HES-SO. \nConsultez [**cette page**](https://www.hes-so.ch/la-hes-so/bibliotheques/travaux-fin-etudes) pour le d\u00e9tails.\n\nEn cas de question, merci de contacter les biblioth\u00e9caires de la HES-SO : bibliotheques(at)hes-so.ch","language":"fre"}],"isDedicated":false}],"language":[{"type":"bf:Language","value":"eng"}],"provisionActivity":[{"type":"bf:Publication","startDate":"2023","statement":[{"type":"bf:Place","label":[{"value":"Sion"}]},{"type":"bf:Agent","label":[{"value":"Haute Ecole d'Ing\u00e9nierie, HES-SO Valais-Wallis"}]},{"type":"Date","label":[{"value":"2023"}]}],"text":{"default":"Sion : Haute Ecole d'Ing\u00e9nierie, HES-SO Valais-Wallis, 2023"}}],"notes":["Haute Ecole d'Ing\u00e9nierie Valais","Syst\u00e8mes industriels - 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2006, vol. 562, p. 3-16"}],"abstracts":[{"value":"Meteorological and climatic processes in mountain regions play a key role in many  environmental systems, in particular the quantity and quality of water that influences  both aquatic ecosystems and economic systems often far beyond the boundaries of  the mountains themselves. This paper will provide a general overview of some of the  particular characteristics of mountain weather and climate, to highlight some of the  unique atmospheric features that are associated with regions of complex topography.  The second part of the paper will focus upon characteristics of climate and climatic  change in the European Alps, a region with a wealth of high quality data that allows an  assessment on how climate and dependent environmental systems have evolved in  the course of the 20th century and how alpine climate may undergo further changes to  \u201cglobal warming\u201d in the 21st century, as the atmosphere responds to increasing levels  of greenhouse gases that are expected in coming decades.","language":"eng"}],"contribution":[{"role":["cre"],"agent":{"type":"bf:Person","preferred_name":"Beniston, Martin"},"affiliation":"Department of Geosciences, University of Fribourg, Switzerland","controlledAffiliation":["University of Fribourg"],"text":"Beniston, Martin"}],"organisation":[{"pid":"unifr","code":"unifr","name":"Universit\u00e9 de Fribourg","_files":[{"key":"UNF_Logo_300pr_neg.png","size":6290,"order":1,"bucket":"892a7e0d-8bd7-4252-b040-4f27bf5497d8","file_id":"ca326183-8b5e-4499-b2b0-4ed4cb87da77","checksum":"md5:0cb5af6ed0da6f44325c3d370fb5fb5d","mimetype":"image/png","version_id":"49dc3678-813f-4fda-b99d-9bc47325ff3d"}],"footer":[{"value":"[Aide & documentation](/unifr/help/)&nbsp;&nbsp;|&nbsp;&nbsp;[D\u00e9poser des articles sur FOLIA](https://webapps.unifr.ch/folia)&nbsp;&nbsp;|&nbsp;&nbsp;[Contact](https://www.unifr.ch/researcher/fr/open-science/open-access/contact.html)","language":"fre"},{"value":"[Help & documentation](/unifr/help/)&nbsp;&nbsp;|&nbsp;&nbsp;[Upload Articles to FOLIA](https://webapps.unifr.ch/folia)&nbsp;&nbsp;|&nbsp;&nbsp;[Contact](https://www.unifr.ch/researcher/en/openscience/open-access/contact.html)","language":"eng"},{"value":"[Hilfe & Dokumentation](/unifr/help/)&nbsp;&nbsp;|&nbsp;&nbsp;[Artikel auf FOLIA hochladen](https://webapps.unifr.ch/folia)&nbsp;&nbsp;|&nbsp;&nbsp;[Kontakt](https://www.unifr.ch/researcher/de/open-science/open-access/kontakt.html)","language":"ger"},{"value":"[Aiuto & documentazione](/unifr/help/)&nbsp;&nbsp;|&nbsp;&nbsp;[Caricare articoli su FOLIA](https://webapps.unifr.ch/folia)&nbsp;&nbsp;|&nbsp;&nbsp;[Contatto](https://www.unifr.ch/researcher/fr/open-science/open-access/contact.html)","language":"ita"}],"_bucket":"892a7e0d-8bd7-4252-b040-4f27bf5497d8","isShared":true,"allowedIps":"134.21.*.*","serverName":"folia.unifr.ch","description":[{"value":"FOLIA est le serveur de d\u00e9p\u00f4t institutionnel de l'Universit\u00e9 de Fribourg et de la Haute Ecole p\u00e9dagogique Fribourg (Suisse). Il fournit un acc\u00e8s libre aux publications des chercheurs et chercheuses de ces deux institutions. FOLIA est g\u00e9r\u00e9 par la Biblioth\u00e8que cantonale et universitaire de Fribourg.\n\n**[D\u00e9poser des articles sur FOLIA en tant que chercheur de l'Universit\u00e9 de Fribourg](https://webapps.unifr.ch/folia)**","language":"fre"},{"value":"FOLIA is the institutional repository of the University of Fribourg and the University of Teacher Education of Fribourg (Switzerland). It provides free access to the publications of the researchers of both institutions. FOLIA is managed by the Biblioth\u00e8que cantonale et universitaire de Fribourg.\n\n**[Upload Articles to FOLIA as a researcher of the University of Fribourg](https://webapps.unifr.ch/folia)**","language":"eng"},{"value":"FOLIA ist das institutionelle Repositorium der Universit\u00e4t Freiburg und der P\u00e4dagogischen Hochschule Freiburg (Schweiz). Es bietet freien Zugang zu den Publikationen der Forschenden dieser beiden Institutionen. FOLIA wird von der Kantons- und Universit\u00e4tsbibliothek Freiburg betreut.\n\n**[Artikel auf FOLIA hochladen als Forscher der Universit\u00e4t Fribourg](https://webapps.unifr.ch/folia)**","language":"ger"},{"value":"FOLIA \u00e8 l'archivio istituzionale dell'Universit\u00e0 di Friburgo e della Alta Scuola Pedagogica di Friburgo (Svizzera ). Fornisce un accesso gratuito alle pubblicazioni dei ricercatrici e ricercatori di queste due istituzioni. FOLIA \u00e8 gestito dalla Biblioth\u00e8que cantonale et universitaire de Fribourg.\n\n**[Upload Articles to FOLIA as a researcher of the University of Fribourg](https://webapps.unifr.ch/folia)**","language":"ita"}],"isDedicated":true,"platformName":"# FOLIA\n#### Fribourg Open Library and 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