Impact of DNA Oxidation on Toxicology: From Quantification to Genomics.
- Wu J Department of Health Sciences and Technology , ETH Zürich , Schmelzbergstrasse 9 , 8092 Zürich , Switzerland.
- Sturla SJ Department of Health Sciences and Technology , ETH Zürich , Schmelzbergstrasse 9 , 8092 Zürich , Switzerland.
- Burrows CJ Department of Chemistry , University of Utah , Salt Lake City , Utah 84112-0850 , United States.
- Fleming AM Department of Chemistry , University of Utah , Salt Lake City , Utah 84112-0850 , United States.
- 2019-02-27
Published in:
- Chemical research in toxicology. - 2019
English
Understanding the toxicological implications of deoxyribonucleic acid (DNA) oxidation arising from cellular oxidative stress depends on identifying DNA oxidation products, their location in the genome, and their interaction with repair, replication, and gene expression.
- Language
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- English
- Open access status
- bronze
- Identifiers
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- DOI 10.1021/acs.chemrestox.9b00046
- PMID 30807111
- Persistent URL
- https://roar.hep-bejune.ch/global/documents/213313
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