Journal article
IgG2/IgG4 subclass deficiency in a patient with chronic mucocutaneous candidiasis and bronchiectases.
- Brägger C Department of Paediatrics, University of Zurich, Switzerland.
- Seger RA
- Aeppli R
- Hallè F
- Hitzig WH
- 1989-12-01
Published in:
- European journal of pediatrics. - 1989
Adult
Bronchiectasis
Candidiasis
Candidiasis, Chronic Mucocutaneous
Dysgammaglobulinemia
Humans
IgG Deficiency
Immunoglobulin G
Male
English
A 22-year-old man with chronic mucocutaneous candidiasis (CMC) and hypothyroidism developed severe bronchiectases following recurrent bronchopneumonia. Immunological investigations revealed IgG2/IgG4 subclass deficiency and absence of antibodies against pneumococcal and Haemophilus polysaccharides. Under regular immunoglobulin substitution every 3 weeks pulmonary symptoms improved markedly.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1007/bf01958272
- PMID 2612503
- Persistent URL
- https://roar.hep-bejune.ch/global/documents/99269
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